Mitragyna hirsuta is sometimes sought when kratom is not available, or it can be mixed to create a blend with a broader spectrum of alkaloids. Kratom may be mixed with other psychoactive drugs, such as caffeine and codeine. Starting in the 2010s, a tea-based cocktail known as “4×100” became popular among some young people across Southeast Asia and especially in Thailand. It is a mix of kratom leaves, cough syrup, Coca-Cola, and ice. Around 2011, people who consumed the cocktail were often viewed more negatively than users of traditional kratom, but not as negatively as users of heroin.
Speciosa are indole alkaloids related to mitragynine, which is a tetracyclic relative of the pentacyclic indole alkaloids, yohimbine and voacangine. In particular, mitragynine and 7-hydroxymitragynine (7-HMG) compose significant proportions of the natural products isolable from M. Speciosa; e.g., in one study, mitragynine was 12% by weight from Malaysian leaf sources, versus 66% from Thai sources, and 7-hydroxymitragynine constituted ~2% by weight. In addition, at least 40 other compounds have been isolated from M. Speciosa leaves, including ~25 additional alkaloids, including raubasine/ajmalicine , corynantheidine , as well as mitraphylline, mitragynine pseudoindoxyl, and rhynchophylline. Anecdotal reports describe increased alertness, physical energy, talkativeness, sociability, sedation, changes in mood, and pain relief following kratom use at various doses.
I will take 1/3 or 1/2 my normal dose of kratom then an hour later take a full dose of Hirsuta (btween 16-25g). The powdered leaf really dries out the body and strips the stomach of moisture. But be warned, it will not totally substitute Kratom so if you only have hirsuta you will still have the wds.
Extracts and leaves have been used to treat coughs, diarrhea, and intestinal infections. They are also used as intestinal deworming agents in Thailand. Mitragyna speciosa (commonly known as kratom, an herbal leaf from a tree of the Rubiaceae family, ) is a tropical evergreen tree in the coffee family native to Southeast Asia. It is indigenous to Thailand, Indonesia, Malaysia, Myanmar, and Papua New Guinea, where it has been used in herbal medicine since at least the nineteenth century. It has also historically been used for chewing, smoking, and tea. Kratom has opioid properties and some stimulant-like effects.
Mitraphylline has also been detected in kratom, as well as a plant known as cat’s claw . Mitraphylline binds to the same opioid receptors as mitragynine and produces similar effects. Hirsuta is referred to among users as kra thum khok, which is pronounced very similar to ‘kratom.’ The plant looks similar with bright green leaves that are somewhat smaller than those found on the kratom plant. But we were curious if perhaps there were trace amounts.
If you’re interested in other plants that share similarities with kratom, then you might want to check these out. Remember that these are medicinal plants, however, and they should be treated with respect. Mitragyna hirsuta is a plant belonging to the Mitragyna genus, the same plant family that kratom belongs to. HHC remains one of the most popular kratom alternatives.
Kratom is an impressive anxiety-supportive supplement when used at the right dose. Learn how kratom works for anxiety & what dose to use. Mitragyna hirsuta can also be dried and ground into powder, much like kratom. This is the most popular way to use the plant in the West. Hydroxylated kratom alkaloids and the unoxidized starting… Hirsuta is great when taken after a small dose of Kratom.
Data on how widely it is used worldwide are lacking, as it is not detected by typical drug-screening tests. Rates of kratom use appear to be increasing among those who have been self-managing chronic pain with opioids purchased without a prescription and are cycling their opioid use. Needs to review the security of your connection before proceeding. Mitragyna hirsuta is one of the most popular kratom alternatives.
Since kra thum khok is less potent, it’s less likely to cause side effects. Studies done on mitraphylline extracted from cat’s claw show that it has a lot of promise. The alkaloid was linked to anti-inflammatory and anti-cancer benefits. While there haven’t been any studies done on mitraphylline extracted from kratom or kra thum khok, there’s no reason that the alkaloid would behave differently.